Ribosomal Protein L19 Is a Prognostic Marker for Human Prostate Cancer

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Ribosomal protein l19 is a prognostic marker for human prostate cancer.

Microquantity differential display analysis of gene expression profiles between benign (PNT2) and malignant (PC3M) human prostate cell lines identified the gene encoding ribosomal protein L19 (RPL19) to be overexpressed in the malignant cells. Northern blot hybridization analysis done on a wide range of human cell lines and tissues confirmed the level of RPL19 mRNA to be 5-fold higher in malign...

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Ribosomal proteins are encoded by a gene family, members of which are overexpressed in human cancers. Many of them have been found, using oligonucleotide microarray hybridization, to be differentially expressed in the faeces of patients with various stages of colorectal cancer (CRC). The gene encoding ribosomal protein L19 (RPL19), a prognostic marker for human prostate cancer, is differentiall...

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ژورنال

عنوان ژورنال: Clinical Cancer Research

سال: 2006

ISSN: 1078-0432,1557-3265

DOI: 10.1158/1078-0432.ccr-05-2445